“Hadrontherapy for Life” Symposium, Caen, March 10/11, 2025–Strategy for the Future–Pediatric Tumors
The symposium "Hadrontherapy for life," held in Caen, on March 10 and 11, 2025, brought together over 100 international experts of heavy ions particle therapy. Clinical aspects of current indications and future strategies were discussed. If protontherapy remains the cornerstone of current strategies dealing with pediatric malignancies, in order to better spare normal tissues from deleterious effects of radiation, heavier ions such as carbon ions could play a role in selected highly radio-resistant processes such as bone and non rhabdomyosrcomas soft tissue sarcomas. A special mention should be made to helium ions tested since 2021 in Europe that mimic protons with further ballistic selectivity. If immediate and early side effects of heavy ions look modest, long-term tolerance still needs to be carefully evaluated, including risks of carcinogenesis.
Authors
- Semi Harrabi (ORCID: https://orcid.org/0000-0003-1195-7150)
- Siamak Haghdoost (ORCID: https://orcid.org/0000-0002-2867-4774)
- Tatsuya Ohno (ORCID: https://orcid.org/0000-0002-6703-3144)
- Emily Light (ORCID: https://orcid.org/0009-0002-0272-9535)
- J. Doyen (ORCID: https://orcid.org/0000-0003-4646-4778)
- Anita Mahajan (ORCID: https://orcid.org/0000-0001-7609-4451)
- Juliette Thariat (ORCID: https://orcid.org/0000-0003-4755-496X)
- Shigeru Yamada (ORCID: https://orcid.org/0000-0002-4271-0209)
- Bradford S. Hoppe (ORCID: https://orcid.org/0000-0002-2312-5418)
- Jacques Balosso (ORCID: https://orcid.org/0000-0003-0714-9003)
- Audrey Larnaudie (ORCID: https://orcid.org/0000-0002-7043-2103)
- Zheng Wang (ORCID: https://orcid.org/0000-0002-2153-1252)
- Arnold Pompoš
- R. Dendale
- Jean‐Louis Habrand
- Anthony Vela
Institutions
- Mayo Clinic (US)
- Gunma University (JP)
- Heidelberg University (DE)
- Centre Hospitalier Universitaire de Grenoble (FR)
- Jacksonville College (US)
- University Hospital Heidelberg (DE)
- Centre François Baclesse (LU)
- National Institutes for Quantum Science and Technology (JP)
- Centre François Baclesse (FR)
- Mayo Clinic in Arizona (US)
- The Christie NHS Foundation Trust (GB)
- Mayo Clinic in Florida (US)
- Centre Antoine Lacassagne (FR)
- Institut Curie (FR)
- The University of Texas Southwestern Medical Center (US)
- Université Grenoble Alpes (FR)
- Université de Caen Normandie (FR)
Publication Details
- Journal
- International Journal of Particle Therapy
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1016/j.ijpt.2025.101286
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 0.00