Stem Cell Secretome Reverse Areca Nut Extract Induced Fibrosis in Human Fibroblast and Patient‐Derived Biopsies
Secretome exhibited promising cytoprotective and anti-fibrotic properties, reduction in cell death, senescence, collagen expression, and oxidative stress. These findings support the potential of secretome as a novel therapeutic candidate for oral submucous fibrosis, meriting further investigation in preclinical and clinical trials.
Authors
- Avinash Sanap (ORCID: https://orcid.org/0000-0003-2535-0958)
- Supriya Kheur (ORCID: https://orcid.org/0000-0002-2440-3547)
- Avinash Kharat (ORCID: https://orcid.org/0000-0002-5647-8340)
- Nishant Mante (ORCID: https://orcid.org/0000-0002-2293-8345)
- Nikhil Pande
- Ramesh Bhonde (ORCID: https://orcid.org/0000-0001-9955-2056)
- Pranjali Potdar
- Bhagyashri Patil‐Takbhate (ORCID: https://orcid.org/0009-0002-7996-3012)
- Nitika Monga
Institutions
- Launceston General Hospital (AU)
- Indian Council of Medical Research (IN)
- Dr. D. Y. Patil Medical College, Hospital and Research Centre (IN)
- Dr. D.Y. Patil Vidyapeeth, Pune (IN)
- Dr D Y Patil Dental College & Hospital (IN)
Publication Details
- Journal
- Journal of Oral Pathology and Medicine
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1111/jop.70090
- Primary Topic
- Oral Health Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00