Single-cell and bulk transcriptome analyses revealed the role of macrophage cholesterol metabolism in atherosclerosis
This study provides a comprehensive understanding of macrophage CM in AS and highlights the potential of FABP4, RNASET2, and FILIP1L as diagnostic hallmark genes and therapeutic targets.
Authors
- Chenxin Liao
- Dajun Chai (ORCID: https://orcid.org/0000-0001-9477-9956)
- Jinxiu Lin (ORCID: https://orcid.org/0000-0003-1035-2993)
- Jiaxing Ke (ORCID: https://orcid.org/0009-0006-8059-6618)
- Lingjia Li (ORCID: https://orcid.org/0009-0000-1150-5811)
- Feng Peng
Institutions
- Fujian Medical University (CN)
- Education Department of Fujian Province (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Lipids in Health and Disease
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1186/s12944-025-02773-6
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00