Assessing lung cancer screening knowledge, attitude, and perceived barriers among high-risk individuals in Jordan: A cross-sectional study

<h2>Abstract</h2><h3>Problem considered</h3> Lung cancer (LC) is a leading cause of cancer-related mortality globally. Early detection through low-dose computed tomography (LDCT) significantly improves prognosis, yet public awareness and screening uptake remain low, particularly in Jordan. This study aims to assess the knowledge, attitudes, and perceived barriers toward LC screening among high-risk individuals in Jordan. <h3>Methods</h3> A cross-sectional study was conducted among 470 high-risk participants, primarily long-term smokers. A validated questionnaire assessed knowledge of LC risk factors, symptoms, and screening methods; attitudes toward early detection; and perceived barriers. Descriptive statistics, bivariate analyses, and multivariate linear regression were used to examine associations between sociodemographic factors and outcome scores. <h3>Results</h3> Participants demonstrated moderate knowledge (mean = 9 ± 5 out of 20), with high awareness of general LC risk factors but limited knowledge of LDCT (25.7 %). Over 90 % supported early detection, yet 27.4 % held fatalistic beliefs. Key barriers included lack of knowledge (86.2 %), unawareness of procedures (84.5 %), time constraints (61.7 %), and fear of diagnosis (54.5 %). Knowledge and attitudes were significantly associated with education, income, employment status, and family history of LC. Multivariate analysis confirmed sociodemographic factors and willingness to screen as strong predictors of engagement. <h3>Conclusion</h3> Despite positive attitudes, there are significant gaps in knowledge and several perceived barriers to LC screening among high-risk individuals. Targeted educational interventions, greater physician involvement, and culturally tailored outreach are crucial to improving screening uptake in this population.