Mediterranean and low-fat diets are equally effective in MASLD resolution at 12 weeks regardless of PNPLA3 genotype: A randomized controlled trial
Weight reduction achieved by MD and LFD is similarly efficient in steatosis and fibrosis reduction, while PNPLA3 genotype does not affect the response to diet. Further studies investigating the impact of diet and nutrigenetics on liver-related outcomes are warranted.
Authors
- Ger H. Koek (ORCID: https://orcid.org/0000-0002-7863-392X)
- Volkan Yumuk (ORCID: https://orcid.org/0000-0001-6463-4916)
- Zeynep Öztürk (ORCID: https://orcid.org/0000-0002-0649-844X)
- Gediz Dogay Us (ORCID: https://orcid.org/0000-0003-0313-8673)
- Özgür M. Koc (ORCID: https://orcid.org/0000-0003-3678-5703)
- Francesco Innocenti (ORCID: https://orcid.org/0000-0001-6113-8992)
- Ayse Eylul Alagoz
Institutions
- Maastricht University (NL)
- Istanbul University-Cerrahpaşa (TR)
- Istanbul Eye Hospital (TR)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1097/hc9.0000000000000856
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35