Oral delivery of dextran-modified albumin nanoparticles loaded with shikonin for targeted therapy of colorectal cancer
Overall, our results suggest that SHK-loaded nanodrugs can effectively target key molecular pathways in CRC and provide a promising strategy for colorectal cancer treatment with advantages such as improved drug stability, tumor-specific targeting, and reduced systemic toxicity.
Authors
- Jingyuan Zhao (ORCID: https://orcid.org/0000-0002-2770-3481)
- Shuai Li (ORCID: https://orcid.org/0000-0002-3492-7176)
- Hong Yuan (ORCID: https://orcid.org/0000-0003-4481-5298)
- Zhen Ren (ORCID: https://orcid.org/0009-0009-2492-7410)
Institutions
- Dalian Medical University (CN)
- Dalian University of Technology (CN)
- Dalian Municipal Central Hospital (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Discover Nano
- Published
- 2025-11-22
- DOI
- https://doi.org/10.1186/s11671-025-04393-6
- Citations
- 1
- Primary Topic
- Bioactive Compounds and Antitumor Agents
- Type
- article
- Field-Weighted Citation Impact
- 1.31