Abelmoschus Manihot flowers inhibit dysbiotic Enterobacteriaceae expansion by promoting Clostridium bolteae-mediated hypoxia restoration
Overall, our study provides evidence that modulating the gut microbiota to restore intestinal hypoxia is a promising therapeutic strategy for suppressing Enterobacteriaceae proliferation in the inflamed gut and for ameliorating intestinal inflammation, which could be applied to other Enterobacteriaceae-related diseases. Video Abstract.
Authors
- Yumeng Wang (ORCID: https://orcid.org/0009-0005-8250-9664)
- Hui Liang (ORCID: https://orcid.org/0000-0002-7372-9957)
- Jin‐Ao Duan (ORCID: https://orcid.org/0000-0001-7109-7848)
- Qinyu Zhang (ORCID: https://orcid.org/0000-0001-8292-938X)
- Shu Zhang (ORCID: https://orcid.org/0009-0000-2223-5706)
- Jianping Li (ORCID: https://orcid.org/0000-0003-4976-4119)
- Jianming Guo (ORCID: https://orcid.org/0009-0007-8408-481X)
- Chengxi Li (ORCID: https://orcid.org/0000-0003-3904-0299)
Institutions
- Nanjing University of Chinese Medicine (CN)
Publication Details
- Journal
- Microbiome
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1186/s40168-025-02246-z
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00