Experience with Linezolid for the Treatment of Rifampin-Susceptible Tuberculosis in San Francisco

Linezolid is recommended for the treatment of rifampin-resistant tuberculosis (TB), but its role in rifampin-susceptible TB (RS-TB) is less understood. In 45 RS-TB patients treated with linezolid, 8 stopped due to adverse events, most commonly cytopenias. Further research is needed on linezolid efficacy, dosing, and adverse event management in RS-TB.

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Publication Details

Journal
Open Forum Infectious Diseases
Published
2025-11-25
DOI
https://doi.org/10.1093/ofid/ofaf714
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Experience with Linezolid for the Treatment of Rifampin-Susceptible Tuberculosis in San Francisco

John D. Szumowski, Allison L. Phillips, Gustavo E. Velásquez, Janice K. Louie
Open Forum Infectious Diseases
Tuberculosis Research and Epidemiology
article

Experience with Linezolid for the Treatment of Rifampin-Susceptible Tuberculosis in San Francisco

John D. Szumowski, Allison L. Phillips, Gustavo E. Velásquez, Janice K. Louie
article en

Abstract

Linezolid is recommended for the treatment of rifampin-resistant tuberculosis (TB), but its role in rifampin-susceptible TB (RS-TB) is less understood. In 45 RS-TB patients treated with linezolid, 8 stopped due to adverse events, most commonly cytopenias. Further research is needed on linezolid efficacy, dosing, and adverse event management in RS-TB.

Open Forum Infectious DiseasesVol. 12(12)
University of California, San Francisco (US), University of California System (US), San Francisco Department of Public Health (US), Global Brain Health Institute (US), Global Solutions for Infectious Diseases (US), University of San Francisco (US)
Openalex Percentile: Top 57%
Tuberculosis Research and Epidemiology
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