A morphomolecular study of 175 ‘ <scp> <i>USP6</i> </scp> ‐associated neoplasms’: The <scp> <i>USP6</i> </scp> fusion partner strongly depends on morphology and location
A significant entity- and location-specific USP6 fusion partner diversity was revealed among the UAN members. This supports the hypothesis that this diversity may be linked to the cell of origin. Additionally, molecular analysis can be valuable in diagnosing non-classical NF.
Authors
- Bram Van Gaever
- Uta Flucke (ORCID: https://orcid.org/0000-0003-0315-4307)
- Fleur Cordier (ORCID: https://orcid.org/0000-0003-0876-3398)
- Maria Dêbiec‐Rychter (ORCID: https://orcid.org/0000-0001-8183-2105)
- Siebe Loontiens (ORCID: https://orcid.org/0000-0002-4602-4580)
- Joni Van der Meulen (ORCID: https://orcid.org/0000-0002-1916-2769)
- Jo Van Dorpe (ORCID: https://orcid.org/0000-0001-8175-2930)
- Franceska Dedeurwaerdere (ORCID: https://orcid.org/0000-0003-4608-1101)
- Sarah Van Belle
- Liesbeth Ferdinande (ORCID: https://orcid.org/0009-0008-4030-761X)
- Raf Sciot (ORCID: https://orcid.org/0000-0003-2244-5839)
- Joost van Gorp
- David Creytens (ORCID: https://orcid.org/0000-0002-6064-1673)
Institutions
- Radboud University Nijmegen (NL)
- Ghent University Hospital (BE)
- Research Foundation - Flanders (BE)
- Radboud University Medical Center (NL)
- Ghent University (BE)
- St. Antonius Ziekenhuis (NL)
- Center for Human Genetics (US)
- Inagro (Belgium) (BE)
- Cancer Research Institute Ghent (BE)
- AZ Delta (BE)
- KU Leuven (BE)
Publication Details
- Journal
- Histopathology
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1111/his.70057
- Primary Topic
- Ubiquitin and proteasome pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fonds Wetenschappelijk Onderzoek
- Universitair Ziekenhuis Gent
- Universiteit Gent
- Vlaamse regering