Effect of Antioxidant Supplementation on Factors of Metabolic Acidosis in Adult Males Participating in High-Intensity CrossFit

This study aims to present a nutritional intervention to prevent metabolic acidosis—a downside of modern high-intensity, short-duration exercise—by investigating the effects of antioxidant supplementation on biomarkers related to acidosis.<br/>Methods<br/>Twenty healthy adult males aged 20–35 who regularly participated in high-intensity CrossFit training were randomly assigned into two groups: an antioxidant supplementation group (IG: In-take Group) and a non-supplementation group (NG: Non-take Group), with 10 participants in each group. Over an 8-week period, all participants engaged in 40-minute CrossFit sessions at 75–95% HRmax. Biomarkers of metabolic acidosis—lactate and uric acid—were measured for all participants. Measurements were taken 10 minutes after the first training session (pre-test) and 10 minutes after the final (32nd) session (post-test) for comparative analysis.<br/>Results<br/>Eight weeks of antioxidant supplementation significantly reduced the rate of increase in blood lactate levels following high-intensity CrossFit exercise in adult males.<br/>Eight weeks of antioxidant supplementation also significantly reduced the rate of increase in uric acid levels in the same context.<br/>Antioxidant supplementation proved effective in preventing metabolic acidosis during high-intensity exercise in adult males.<br/>Conclusion<br/>This study demonstrates that antioxidant supplementation can significantly reduce metabolic acidosis indicators such as lactate and uric acid in high-intensity, short-duration exercise like CrossFit, which is increasingly popular among modern adults. Therefore, it may be suggested as a viable strategy to prevent exercise-induced metabolic acidosis.