Human herpesvirus 7 induced aseptic meningitis in an immunocompetent adult presenting with unusual neurological symptoms: a case report
We report a rare case of viral meningitis induced by HHV-7 in a 37-year-old immunocompetent female, whose initial symptoms were unusual, presenting primarily with lower limb pain and numbness. Laboratory tests revealed HHV-7 deoxyribonucleic acid (DNA) in the CSF, confirming the diagnosis of aseptic meningitis. This case emphasizes the importance of considering HHV-7 in the differential diagnosis of viral meningitis, even without classic systemic signs. Despite the absence of specific antiviral therapy for HHV-7, supportive care remains effective. This case adds to the growing evidence on HHV-7 as an under-recognized cause of aseptic meningitis, particularly in immunocompetent individuals.
Authors
- Cam Anh Nguyen Le (ORCID: https://orcid.org/0009-0001-7647-3483)
- Thi Hong Phuong Nguyen (ORCID: https://orcid.org/0009-0001-1328-2583)
- Pham Mai Anh Nguyen (ORCID: https://orcid.org/0009-0001-4650-6678)
Institutions
- Vinmec Times City International Hospital (VN)
- VinUniversity (VN)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1186/s12985-025-03025-w
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00