Can the detection of serum glutathione reductase serve as an effective complement to traditional tumor biomarkers in clinical laboratory medicine for patients with hepatocellular carcinoma?
The detection of serum GR can serve as an effective complement to traditional tumor biomarkers in clinical laboratory medicine for HCC patients, particularly those with AFP-negative HCC. The combined detection of GR, AFP, PIVKA-Ⅱ, CEA, and CA19-9 can significantly enhance the diagnostic performance of HCC patients.
Authors
- Hua Huang (ORCID: https://orcid.org/0000-0001-6111-8019)
- Qingzhu Zheng
- Xiaohong Xu (ORCID: https://orcid.org/0009-0000-9736-0712)
- Siyan Chen (ORCID: https://orcid.org/0009-0002-1720-8660)
- Yingping Cao (ORCID: https://orcid.org/0000-0002-0281-1515)
- Jiamiao Weng
Institutions
- Fujian Medical University (CN)
- Fujian Provincial Cancer Hospital (CN)
- Union Hospital (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1186/s12885-025-15383-3
- Primary Topic
- Sulfur Compounds in Biology
- Type
- article
- Field-Weighted Citation Impact
- 0.00