Immune cell-based transcriptomic Mendelian randomization and colocalization study on type 1 diabetes
Our findings provide novel avenues for drug development and repurposing to prevent or delay T1D onset.
Authors
- Liam Gaziano (ORCID: https://orcid.org/0000-0003-2059-8081)
- Elias Allara (ORCID: https://orcid.org/0000-0002-1634-8330)
- Julie Sklar (ORCID: https://orcid.org/0000-0001-5105-2538)
- Adam S. Butterworth (ORCID: https://orcid.org/0000-0002-6915-9015)
- Grace Nickel
- David Stacey (ORCID: https://orcid.org/0000-0002-9392-9235)
Institutions
- Harvard University (US)
- University of South Australia (AU)
- University of Cambridge (GB)
- British Heart Foundation (GB)
- South Australian Health and Medical Research Institute (AU)
- Health Data Research UK (GB)
- Quinnipiac University (US)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1186/s12916-025-04527-8
- Primary Topic
- Diabetes and associated disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00