Hemophagocytic Lymphohistiocytosis in a Pediatric Lung Transplant Recipient

Solid organ transplantation appears to raise a patient's risk of developing HLH, although the underlying mechanisms are unclear. Literature review suggests patients are most likely to develop this complication within the first few months of transplantation, and a high index of suspicion must be maintained in those who present with a febrile illness of unclear etiology. Standard HLH treatment protocols may not be applicable to this patient population, and further studies are needed.

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Publication Details

Journal
Pediatric Transplantation
Published
2025-11-25
DOI
https://doi.org/10.1111/petr.70232
Primary Topic
Autoimmune and Inflammatory Disorders Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Hemophagocytic Lymphohistiocytosis in a Pediatric Lung Transplant Recipient

Dallas Parrish, María C. Gazzaneo, Anna Schrader, Ernestina Melicoff et al.
Pediatric Transplantation
Autoimmune and Inflammatory Disorders Research
article

Hemophagocytic Lymphohistiocytosis in a Pediatric Lung Transplant Recipient

Dallas Parrish, María C. Gazzaneo, Anna Schrader, Ernestina Melicoff, Nahir Cortes‐Santiago, Sunil Chickmagalur, David McNeill
article en

Abstract

Solid organ transplantation appears to raise a patient's risk of developing HLH, although the underlying mechanisms are unclear. Literature review suggests patients are most likely to develop this complication within the first few months of transplantation, and a high index of suspicion must be maintained in those who present with a febrile illness of unclear etiology. Standard HLH treatment protocols may not be applicable to this patient population, and further studies are needed.

Pediatric TransplantationVol. 29(8)
Baylor College of Medicine (US), Texas Children's Hospital (US)
Openalex Percentile: Top 52%
Autoimmune and Inflammatory Disorders Research
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Hemophagocytic Lymphohistiocytosis in a Pediatric Lung Transplant Recipient — Dallas Parrish, María C. Gazzaneo, et al. · Pediatric Transplantation (2025) | TGRS Research Map | TGRS