Prognostic implication of serum levels of IL-6 and IL-10 in children and adolescents with aggressive mature B-cell non-Hodgkin lymphoma
Our study suggests that elevated serum IL-6 and IL-10 levels at diagnosis are associated with poor prognosis in pediatric mature B-NHL and may have the potential to inform risk stratification. Future prospective, multi-center studies are required to validate these findings.
Authors
- Suying Lü (ORCID: https://orcid.org/0000-0001-8117-3533)
- Juan Wang (ORCID: https://orcid.org/0000-0002-3456-4272)
- Xiaofei Sun (ORCID: https://orcid.org/0000-0002-9396-2414)
- Junting Huang (ORCID: https://orcid.org/0000-0002-2448-5837)
- Zijun Zhen (ORCID: https://orcid.org/0000-0002-4442-0897)
- Zhiqing Wei (ORCID: https://orcid.org/0000-0001-7940-2739)
- Chenggong Zeng (ORCID: https://orcid.org/0000-0002-2224-6031)
- Yizhuo Zhang (ORCID: https://orcid.org/0000-0002-6128-3476)
- Xiaofei Sun (ORCID: https://orcid.org/0000-0002-4818-8853)
- Jia Zhu (ORCID: https://orcid.org/0000-0003-3987-3557)
Institutions
- Sun Yat-sen University (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1186/s12885-025-15377-1
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00