Impact of LDL-C and apolipoprotein B level discordance and associated lipoprotein particle alterations on cardiovascular outcomes in a large primary prevention population
ApoB is a more comprehensive marker of cardiovascular risk than LDL-C. The higher cardiovascular risk in discordantly high ApoB individuals was partly mediated by VLDL; however, no conclusive evidence indicated that VLDL provides additional prognostic value beyond triglyceride measurements alone.
Authors
- Wenbo Ding (ORCID: https://orcid.org/0000-0003-1360-4922)
- Kefei Dou (ORCID: https://orcid.org/0000-0002-8372-6338)
- Zixiang Ye
- Lijian Gao
- Ying Gao (ORCID: https://orcid.org/0000-0002-7035-2883)
- Yanjun Song
- Yuan Du (ORCID: https://orcid.org/0000-0002-9872-268X)
- Yuan‐Lin Guo (ORCID: https://orcid.org/0000-0002-7159-0189)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Fu Wai Hospital (CN)
Publication Details
- Journal
- European Journal of Preventive Cardiology
- Published
- 2025-11-22
- DOI
- https://doi.org/10.1093/eurjpc/zwaf750
- Citations
- 1
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- National Natural Science Foundation of China