<scp>TGF</scp> ‐β1 Up‐Regulates <scp>PLAU</scp> Expression to Promote Invasion and Migration of Oral Squamous Cell Carcinoma

PLAU acts as a key oncogenic driver in OSCC and may serve as a potential diagnostic and prognostic biomarker. More importantly, the TGF-β1-PLAU axis may offer new therapeutic targets for OSCC treatment.

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Publication Details

Journal
Journal of Oral Pathology and Medicine
Published
2025-11-24
DOI
https://doi.org/10.1111/jop.70091
Primary Topic
TGF-β signaling in diseases
Type
article
Field-Weighted Citation Impact
0.00
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TGF ‐β1 Up‐Regulates PLAU Expression to Promote Invasion and Migration of Oral Squamous Cell Carcinoma

Xiaoxu Nan, Juanjuan Han, Changyue Liu, Honglan Wang, Gaoren Lin, Ying Liu, Han Liu, Dandan Zhang, Jiaming Liu
article en

Abstract

PLAU acts as a key oncogenic driver in OSCC and may serve as a potential diagnostic and prognostic biomarker. More importantly, the TGF-β1-PLAU axis may offer new therapeutic targets for OSCC treatment.

Journal of Oral Pathology and MedicineVol. 55(3)
North Sichuan Medical University (CN), Wenzhou Medical University (CN), Affiliated Hospital of North Sichuan Medical College (CN)
Openalex Percentile: Top 67%
TGF-β signaling in diseases
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