Mortality in isolated polymyalgia rheumatica and giant cell arteritis is not increased: evidence from cohort data

A recent study published in Arthritis Research and Therapy by Tengesdal et al. reported that patients with isolated polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) do not have increased all-cause mortality compared with the general population. Regarding this, we present data from our own previous investigation in northwest Spain, which also showed no increased mortality in 185 patients with PMR or 109 patients with biopsy-confirmed GCA. In this regard, in the northwest Spanish GCA group, mortality was primarily due to cardiovascular causes and was comparable to that of the general population. These findings support the conclusion that neither PMR nor GCA significantly affects life expectancy when appropriately diagnosed and treated.

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Publication Details

Journal
Clinical and Experimental Medicine
Published
2025-11-25
DOI
https://doi.org/10.1007/s10238-025-01884-9
Primary Topic
Vasculitis and related conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

Mortality in isolated polymyalgia rheumatica and giant cell arteritis is not increased: evidence from cohort data

Carlos Garcı́a-Porrúa, Miguel Ángel González-Gay
Clinical and Experimental Medicine
Vasculitis and related conditions
article

Mortality in isolated polymyalgia rheumatica and giant cell arteritis is not increased: evidence from cohort data

Carlos Garcı́a-Porrúa, Miguel Ángel González-Gay
article en

Abstract

A recent study published in Arthritis Research and Therapy by Tengesdal et al. reported that patients with isolated polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) do not have increased all-cause mortality compared with the general population. Regarding this, we present data from our own previous investigation in northwest Spain, which also showed no increased mortality in 185 patients with PMR or 109 patients with biopsy-confirmed GCA. In this regard, in the northwest Spanish GCA group, mortality was primarily due to cardiovascular causes and was comparable to that of the general population. These findings support the conclusion that neither PMR nor GCA significantly affects life expectancy when appropriately diagnosed and treated.

Clinical and Experimental MedicineVol. 26(1)
Universidad de Cantabria (ES), Hospital Universitario Fundación Jiménez Díaz (ES), Hospital Universitario Lucus Augusti (ES)
Openalex Percentile: Top 46%
Vasculitis and related conditions
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