Respiratory Failure Due to Bilateral Vocal Fold Paralysis Following Laparoscopic Cholecystectomy: A Rare Presentation of Myasthenia Gravis

Myasthenia gravis (MG) is an autoimmune disorder affecting the neuromuscular junctions. A 50-year-old woman with well-controlled MG developed stridor and respiratory failure on the first postoperative day after undergoing laparoscopic cholecystectomy with total intravenous anesthesia and sugammadex reversal. During orotracheal intubation, bronchoscopy revealed bilateral vocal fold paralysis in the adducted position. After failed extubation attempts, tracheostomy was required. The patient improved with optimized MG management and was discharged after three weeks. This rare MG manifestation emphasizes the importance of early stridor recognition, difficult airway preparedness, and adherence to American Society of Anesthesiologists guidelines for airway management and bronchoscopy.

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Publication Details

Journal
Cureus
Published
2025-11-24
DOI
https://doi.org/10.7759/cureus.97706
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
Field-Weighted Citation Impact
0.00

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article

Respiratory Failure Due to Bilateral Vocal Fold Paralysis Following Laparoscopic Cholecystectomy: A Rare Presentation of Myasthenia Gravis

Cláudia Regina Machado, Bruno Santiago, Vitor Alves Felippe, Gabriela Gerenutti De Sousa et al.
Cureus
Myasthenia Gravis and Thymoma
article

Respiratory Failure Due to Bilateral Vocal Fold Paralysis Following Laparoscopic Cholecystectomy: A Rare Presentation of Myasthenia Gravis

Cláudia Regina Machado, Bruno Santiago, Vitor Alves Felippe, Gabriela Gerenutti De Sousa, Marcos Adriano Lessa
article en

Abstract

Myasthenia gravis (MG) is an autoimmune disorder affecting the neuromuscular junctions. A 50-year-old woman with well-controlled MG developed stridor and respiratory failure on the first postoperative day after undergoing laparoscopic cholecystectomy with total intravenous anesthesia and sugammadex reversal. During orotracheal intubation, bronchoscopy revealed bilateral vocal fold paralysis in the adducted position. After failed extubation attempts, tracheostomy was required. The patient improved with optimized MG management and was discharged after three weeks. This rare MG manifestation emphasizes the importance of early stridor recognition, difficult airway preparedness, and adherence to American Society of Anesthesiologists guidelines for airway management and bronchoscopy.

CureusVol. 17(11)
University of Iowa (US), Universidade do Estado do Rio de Janeiro (BR), Hospital do Câncer III (BR), Hospital Universitário Clementino Fraga Filho (BR), Instituto Nacional de Câncer - INCA (BR)
Universidade do Estado do Rio de Janeiro
Openalex Percentile: Top 50%
Myasthenia Gravis and Thymoma
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