Investigating the pathogenesis of urolithiasis through gut microbiome, plasma metabolome and inflammatory proteome: a mediation Mendelian randomization study
The present MR analysis provides evidence supporting causal relationships between specific GM taxa and urolithiasis, with plasma metabolites and inflammatory proteins emerging as potential mediators.
Authors
- Zongyao Hao (ORCID: https://orcid.org/0009-0002-1586-5093)
- Lingsong Tao (ORCID: https://orcid.org/0009-0004-5813-7584)
- Yuexian Xu (ORCID: https://orcid.org/0000-0003-0986-5505)
- Yi Liu (ORCID: https://orcid.org/0000-0002-2051-440X)
- Weiyu Zhu
- Guoxiang Li (ORCID: https://orcid.org/0000-0002-8265-5996)
- Guanwei Wu
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Anhui Normal University (CN)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1186/s13148-025-02014-8
- Primary Topic
- Kidney Stones and Urolithiasis Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00