Real-world insights into the prevalence and prognostic significance of trophoblast cell-surface antigen 2 and folate receptor alpha in uterine carcinosarcoma
Complete resection and advanced stage were suggested as prognostic factors in UCS. FRα and Trop-2 are increasingly recognized as therapeutic targets and their elevated expression levels in the epithelial component of UCS are promising, although not associated with prognosis in this cohort.
Authors
- Lucas Zanetti de Albuquerque (ORCID: https://orcid.org/0000-0003-4945-1788)
- Andréia Cristina de Melo (ORCID: https://orcid.org/0000-0002-1201-4333)
- I. A. Small (ORCID: https://orcid.org/0000-0003-0598-9295)
- Jessé Lopes da Silva (ORCID: https://orcid.org/0000-0002-0790-9917)
- Luís Felipe Leite (ORCID: https://orcid.org/0009-0006-8347-1212)
- Gustavo Guitmann
- Fabiana Resende Rodrigues (ORCID: https://orcid.org/0000-0001-5062-1065)
- Priscila Valverde Fernandes (ORCID: https://orcid.org/0000-0002-0196-4755)
Institutions
- Hospital do Câncer III (BR)
- Instituto Nacional de Câncer - INCA (BR)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1186/s12885-025-15298-z
- Primary Topic
- Uterine Myomas and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00