The Japanese Lead Extraction Registry (J‐ <scp>LEX</scp> ): Annual Report in 2024

The Japanese Heart Rhythm Society established a nationwide, mandatory, multi-center, prospective, observational registry of transvenous lead extraction (TLE) named the Japanese lead extraction registry (J-LEX) in 2018. As of the end of 2024, a cumulative total of approximately 5400 cases has been registered across 140 participating centers since 2018. The registry includes all consecutive transvenous extractions, excluding surgical-only cases. The indication of TLE was an infection in 54.5%, and the guideline classification was class I in 59.8% and class IIa in 21.8%. As for non-infectious indications, TLE is performed for abandoned leads in case of lead failure or device upgrade, and for lead-related trouble such as pain, vessel stenosis or occlusion, too many leads, tricuspid valve regurgitation, and difficulty with radiation therapy. In 2024, the TLE procedure was attempted on patients with a median age of 71.3 years, female in 32.7%, in the hybrid operating room in 73.3%, and in a standard OR with a C-arm fluoroscope in 11.5%. The average implantation duration of the target leads was 8.5 years. Complete removal was achieved in 96.7% of the target leads, and clinical success in 97.3% of the patients. Perioperative complications were observed in 4.8% of the patients. Three patients died during a TLE operation, and 11 patients died in-hospital (cardiac death in three patients and non-cardiac death in eight patients).

Authors

Institutions

Publication Details

Journal
Journal of Arrhythmia
Published
2025-11-24
DOI
https://doi.org/10.1002/joa3.70229
Primary Topic
Cardiac pacing and defibrillation studies
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

The Japanese Lead Extraction Registry (J‐ LEX ): Annual Report in 2024

Akihiko Nogami, Katsuhide Hayashi, Wataru Shimizu, Morio Shoda et al.
Journal of Arrhythmia
Cardiac pacing and defibrillation studies
article

The Japanese Lead Extraction Registry (J‐ LEX ): Annual Report in 2024

Akihiko Nogami, Katsuhide Hayashi, Wataru Shimizu, Morio Shoda, Haruka Matsuura, Nobuhiro Nishii, Hiroshi Tada, Koshiro Kanaoka, Masahiko Goya, Yoshihiro Miyamoto, KENGO FUKUSHIMA KUSANO, Masahiko Takagi, Katsuhiko Imai, Yoji Okamoto, Yuji Narita, Mitsuru Wada, Hitoshi Minamiguchi
article en

Abstract

The Japanese Heart Rhythm Society established a nationwide, mandatory, multi-center, prospective, observational registry of transvenous lead extraction (TLE) named the Japanese lead extraction registry (J-LEX) in 2018. As of the end of 2024, a cumulative total of approximately 5400 cases has been registered across 140 participating centers since 2018. The registry includes all consecutive transvenous extractions, excluding surgical-only cases. The indication of TLE was an infection in 54.5%, and the guideline classification was class I in 59.8% and class IIa in 21.8%. As for non-infectious indications, TLE is performed for abandoned leads in case of lead failure or device upgrade, and for lead-related trouble such as pain, vessel stenosis or occlusion, too many leads, tricuspid valve regurgitation, and difficulty with radiation therapy. In 2024, the TLE procedure was attempted on patients with a median age of 71.3 years, female in 32.7%, in the hybrid operating room in 73.3%, and in a standard OR with a C-arm fluoroscope in 11.5%. The average implantation duration of the target leads was 8.5 years. Complete removal was achieved in 96.7% of the target leads, and clinical success in 97.3% of the patients. Perioperative complications were observed in 4.8% of the patients. Three patients died during a TLE operation, and 11 patients died in-hospital (cardiac death in three patients and non-cardiac death in eight patients).

Journal of ArrhythmiaVol. 41(6)
University of Fukui (JP), Kansai Medical University (JP), Heart Rhythm Society (US), Okayama University (JP), University of Occupational and Environmental Health Japan (JP), New Tokyo Hospital (JP), National Cerebral and Cardiovascular Center (JP), Akebono Clinic (JP), Okayama Psychiatric Medical Center (JP), The Arrhythmia Institute (US), Tokyo Women's Medical University (JP), Mita Hospital (JP), Kure Medical Center (JP), Nagoya University (JP)
Heart Rhythm Society
Openalex Percentile: Top 47%
Cardiac pacing and defibrillation studies
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.