Early Initiation of TNF Inhibitors for Tubulointerstitial Nephritis and Uveitis (TINU)

TNFi controlled ocular and renal inflammation in TINU. Furthermore, some patients fail antimetabolite therapy and experience side effects of prolonged corticosteroid therapy. We recommend early and even first-line usage of TNFi as corticosteroid-sparing therapy with or without antimetabolites.

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Publication Details

Journal
Ocular Immunology and Inflammation
Published
2025-11-24
DOI
https://doi.org/10.1080/09273948.2025.2592067
Primary Topic
Nephrotoxicity and Medicinal Plants
Type
article
Field-Weighted Citation Impact
0.00
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article

Early Initiation of TNF Inhibitors for Tubulointerstitial Nephritis and Uveitis (TINU)

René G. VanDeVoorde, Bin Song, T. Brent Graham, Sapna Gangaputra
Ocular Immunology and Inflammation
Nephrotoxicity and Medicinal Plants
article

Early Initiation of TNF Inhibitors for Tubulointerstitial Nephritis and Uveitis (TINU)

René G. VanDeVoorde, Bin Song, T. Brent Graham, Sapna Gangaputra
article en

Abstract

TNFi controlled ocular and renal inflammation in TINU. Furthermore, some patients fail antimetabolite therapy and experience side effects of prolonged corticosteroid therapy. We recommend early and even first-line usage of TNFi as corticosteroid-sparing therapy with or without antimetabolites.

Ocular Immunology and InflammationVol. 34(1)
Monroe Carell Jr. Children's Hospital (US), Vanderbilt University (US), Monroe Carell Jr. Children's Hospital (US), Vanderbilt Health (US)
Openalex Percentile: Top 49%
Nephrotoxicity and Medicinal Plants
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