Effect of Targeted Aspirin Administration Based on First Trimester Combined Screening for Preeclampsia on Preterm Birth: An Interrupted Time Series Analysis
First-trimester screening for preterm preeclampsia identifies women at higher risk for both preterm preeclampsia and PTB. While aspirin prophylaxis and serial assessments improve some perinatal outcomes, they do not significantly reduce spontaneous or iatrogenic PTB rates. Additional interventions will be needed to achieve a substantial reduction in PTB rates in a high-risk population.
Authors
- M. Minopoli (ORCID: https://orcid.org/0000-0002-8681-4501)
- B. Thilaganathan (ORCID: https://orcid.org/0000-0002-5531-4301)
- Ana Pinas
- Claire Pegorie (ORCID: https://orcid.org/0009-0009-1286-415X)
- Alicia Martínez‐Varea (ORCID: https://orcid.org/0000-0002-7600-4281)
- Pilar Palmrich (ORCID: https://orcid.org/0000-0003-2449-2575)
Institutions
- St George's, University of London (GB)
- St George’s University Hospitals NHS Foundation Trust (GB)
- Hospital Universitari i Politècnic La Fe (ES)
- Medical University of Vienna (AT)
Publication Details
- Journal
- BJOG An International Journal of Obstetrics & Gynaecology
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1111/1471-0528.70100
- Citations
- 1
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 2.06