Identification of ITGA2 as a methylation-regulated oncogene through a CeRNA network in papillary thyroid carcinoma
This study established a ceRNA regulatory network in PTC and identified ITGA2 as a potential therapeutic target. Its dysregulated expression is closely associated with epigenetic alterations, offering new insights into the molecular mechanisms of PTC progression.
Authors
- Song Ni (ORCID: https://orcid.org/0009-0009-8478-8280)
- Yiming Zhu (ORCID: https://orcid.org/0000-0003-2353-5713)
- Shaoyan Liu (ORCID: https://orcid.org/0000-0002-7422-4248)
- Guoliang Wu
- Xinyu Wang (ORCID: https://orcid.org/0000-0001-7549-2845)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- National Cancer Center (US)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1007/s12672-025-04129-z
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00