Allocryptopine, tetrahydropalmatine, and tetrahydroberberine N-oxide alkaloids alleviate cellular stress by modulating calcium homeostasis and the MAPK and akt/GSK-3β/tau signaling pathways

These findings suggest that the GGAE exerts a comprehensive neuroprotective effect, positioning it as a promising therapeutic candidate for the treatment of NDs.

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Journal
Frontiers in Pharmacology
Published
2025-11-25
DOI
https://doi.org/10.3389/fphar.2025.1589390
Primary Topic
Berberine and alkaloids research
Type
article
Field-Weighted Citation Impact
0.00

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article

Allocryptopine, tetrahydropalmatine, and tetrahydroberberine N-oxide alkaloids alleviate cellular stress by modulating calcium homeostasis and the MAPK and akt/GSK-3β/tau signaling pathways

Serap Nigdelioglu Dolanbay, Belma Aslım
Frontiers in Pharmacology
Berberine and alkaloids research
article

Allocryptopine, tetrahydropalmatine, and tetrahydroberberine N-oxide alkaloids alleviate cellular stress by modulating calcium homeostasis and the MAPK and akt/GSK-3β/tau signaling pathways

Serap Nigdelioglu Dolanbay, Belma Aslım
article en

Abstract

These findings suggest that the GGAE exerts a comprehensive neuroprotective effect, positioning it as a promising therapeutic candidate for the treatment of NDs.

Frontiers in PharmacologyVol. 16
Gazi University (TR)
Gazi Üniversitesi
Openalex Percentile: Top 60%
Berberine and alkaloids research
DOIOpen Access PDFOpenAlex
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Allocryptopine, tetrahydropalmatine, and tetrahydroberberine N-oxide alkaloids alleviate cellular stress by modulating calcium homeostasis and the MAPK and akt/GSK-3β/tau signaling pathways — Serap Nigdelioglu Dolanbay, Belma Aslım · Frontiers in Pharmacology (2025) | TGRS Research Map | TGRS