Identification of locally advanced rectal cancer-related genes based on transcriptome and mendelian randomization analysis with biological validation
This study offers new insights into the molecular mechanisms underlying LARC pathogenesis and identifies potential therapeutic targets.
Authors
- Jie Yang (ORCID: https://orcid.org/0000-0002-8393-3580)
- Taotao Lao (ORCID: https://orcid.org/0000-0001-9207-4071)
- Qianyun Ma
- Yongqiang Wang (ORCID: https://orcid.org/0000-0002-8149-1002)
- Hua Chen (ORCID: https://orcid.org/0000-0002-6461-0778)
- Jie Wang (ORCID: https://orcid.org/0000-0002-5852-9754)
Institutions
- Jiangsu University (CN)
- Huaian First People’s Hospital (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- First People's Hospital of Kunshan (CN)
- Traditional Chinese Medicine Hospital of Kunshan (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-25
- DOI
- https://doi.org/10.3389/fimmu.2025.1675788
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Jiangsu University