The evolution and significance of embolization efficiency index (EEI) during transcatheter hepatic arterial embolization procedure: a pilot study based on computational fluid dynamics

This proof-of-concept study suggests that, in this model, EEI is primarily influenced by outlet pressure and vascular anatomy, rather than inflow dynamics. These findings call into question the conventional emphasis on flow modulation, pointing to the potential value of pressure-aware strategies and superselective catheter placement near targets. Based on the analyzed case, the study offers quantitative thresholds and spatial EEI gradients that could help refine TAE precision and potentially reduce complications. With further validation, integrating such CFD-based EEI metrics into procedural planning may contribute to standardizing embolization protocols.

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Publication Details

Journal
Frontiers in Bioengineering and Biotechnology
Published
2025-11-25
DOI
https://doi.org/10.3389/fbioe.2025.1638266
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
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article

The evolution and significance of embolization efficiency index (EEI) during transcatheter hepatic arterial embolization procedure: a pilot study based on computational fluid dynamics

Quan Qi, Zixuan Wang, Yi-Fan Zhao
Frontiers in Bioengineering and Biotechnology
Hepatocellular Carcinoma Treatment and Prognosis
article

The evolution and significance of embolization efficiency index (EEI) during transcatheter hepatic arterial embolization procedure: a pilot study based on computational fluid dynamics

Quan Qi, Zixuan Wang, Yi-Fan Zhao
article en

Abstract

This proof-of-concept study suggests that, in this model, EEI is primarily influenced by outlet pressure and vascular anatomy, rather than inflow dynamics. These findings call into question the conventional emphasis on flow modulation, pointing to the potential value of pressure-aware strategies and superselective catheter placement near targets. Based on the analyzed case, the study offers quantitative thresholds and spatial EEI gradients that could help refine TAE precision and potentially reduce complications. With further validation, integrating such CFD-based EEI metrics into procedural planning may contribute to standardizing embolization protocols.

Frontiers in Bioengineering and BiotechnologyVol. 13
Shihezi University (CN), Qingdao University (CN), Qingdao Municipal Hospital (CN)
Openalex Percentile: Top 52%
Hepatocellular Carcinoma Treatment and Prognosis
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The evolution and significance of embolization efficiency index (EEI) during transcatheter hepatic arterial embolization procedure: a pilot study based on computational fluid dynamics — Quan Qi, Zixuan Wang, et al. · Frontiers in Bioengineering and Biotechnology (2025) | TGRS Research Map | TGRS