Rotational Thromboelastometry ( <scp>ROTEM</scp> ) Versus Conventional Coagulation Tests in Cirrhosis: Can We Reduce Plasma Transfusion Without <scp>ROTEM</scp> ?
ROTEM correlates strongly with CCTs and does not overcome their limitations in detecting rebalanced hemostasis. Prophylactic transfusions based solely on abnormal ROTEM or CCTs should be avoided. However, increasing transfusion thresholds to PT-R > 1.8 and platelet count < 40 × 10<sup>9</sup>/L during active bleeding may help reduce unnecessary transfusions.
Authors
- Nuanrat Cheerasiri (ORCID: https://orcid.org/0000-0002-7470-5340)
- Ratchaneekorn Jantasing
- Ponlapat Rojnuckarin (ORCID: https://orcid.org/0000-0001-7912-1996)
- Rapat Pittayanon (ORCID: https://orcid.org/0000-0001-6407-5245)
Institutions
- Chulalongkorn University (TH)
- King Chulalongkorn Memorial Hospital (TH)
Publication Details
- Journal
- Journal of Clinical Laboratory Analysis
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1002/jcla.70130
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00