Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum
These findings collectively demonstrate that Bacillomycin D-C16 inhibits <i>F. oxysporum</i> growth through multifaceted mechanisms involving transcriptional regulation, mitochondrial impairment, ROS accumulation, and interference with DNA replication.
Authors
- Yuanhong Li (ORCID: https://orcid.org/0000-0001-5526-4706)
- Zhaoxin Lu (ORCID: https://orcid.org/0000-0001-9288-7419)
- Xiangmei Ren
- Yang Jiao
- Yu Zheng (ORCID: https://orcid.org/0009-0001-5466-7762)
- Li Zhou (ORCID: https://orcid.org/0000-0001-5296-1469)
- Hua Jiang (ORCID: https://orcid.org/0000-0002-2433-3753)
- Shiqin Wu
- Fuxing Lin
Institutions
- Nanjing Agricultural University (CN)
- Xuzhou Medical College (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-11-25
- DOI
- https://doi.org/10.3389/fmicb.2025.1698200
- Primary Topic
- Microbial Natural Products and Biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Xuzhou Medical University