Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study
Adjunctive memantine was well tolerated in people with epilepsy regarding seizure control and other AEs. Previous warnings might have been disproportionate. Large-scale, randomized trials are required to confirm this and further elucidate its efficacy profiles in epilepsy.
Authors
- Weixi Xiong (ORCID: https://orcid.org/0000-0001-6835-8664)
- Josemir W. A. S. Sander (ORCID: https://orcid.org/0000-0001-6041-9661)
- P Wang (ORCID: https://orcid.org/0000-0002-9086-6419)
- Dong Chi Zhou (ORCID: https://orcid.org/0000-0001-7101-4125)
- Lu Lu (ORCID: https://orcid.org/0000-0003-3717-5237)
- Qi Zhang (ORCID: https://orcid.org/0000-0002-7238-8134)
- Hui Gao (ORCID: https://orcid.org/0000-0001-5096-7023)
- Jing Xiao (ORCID: https://orcid.org/0000-0001-7623-6309)
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Epilepsy Society (GB)
Publication Details
- Journal
- Annals of Clinical and Translational Neurology
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1002/acn3.70262
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research
- University College London
- National Natural Science Foundation of China
- Sichuan University
- National Key Research and Development Program of China
- West China Hospital, Sichuan University