Transcription factor FOXC2 regulates miR-145/ADAMTS5 axis to inhibit angiogenesis in hepatocellular carcinoma via circular RNA 0002898
Our findings collectively elucidate the regulatory role, functional significance, and underlying mechanism of cyclic RNA0002898 in HCC, a previously uncharted relationship. The potential prognostic implications of cyclic RNA0002898 and its therapeutic potential as a target in HCC warrant further investigation.
Authors
- Jiangbei Yuan (ORCID: https://orcid.org/0000-0002-7497-5770)
- Qiaoqiao Yin
- Chengan Xu (ORCID: https://orcid.org/0000-0003-4761-6518)
- Wei Zheng (ORCID: https://orcid.org/0000-0003-1034-0757)
- Qiang He
- Hongying Pan (ORCID: https://orcid.org/0000-0002-8433-3851)
- Fei Lv (ORCID: https://orcid.org/0000-0002-2261-368X)
- Liping Wu (ORCID: https://orcid.org/0000-0003-2660-3486)
- Zengxiang Pan (ORCID: https://orcid.org/0000-0002-4344-0968)
- Jianli Yu
- Yue Zhao
Institutions
- Zhejiang Chinese Medical University (CN)
- Hangzhou Medical College (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1186/s12885-025-15171-z
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00