Uncovering the neurological substrates underlying restlessness in cluster headache - A functional MRI study
Our fMRI findings suggest that the neurological substrates of restlessness in CH involve the LC and SNpc rather than the core aggression network. Weakened connectivity from the SNpc to the superior frontal cortex may represent the downstream pathway contributing to restlessness in CH.
Authors
- Mei‐Chun Chen (ORCID: https://orcid.org/0000-0002-7125-4003)
- Chia‐Chun Chiang (ORCID: https://orcid.org/0000-0001-7802-7172)
- C. Geoffrey Lau (ORCID: https://orcid.org/0000-0001-9750-2514)
- Yung-Lin Chen
- Jr‐Wei Wu (ORCID: https://orcid.org/0000-0003-0952-9608)
- Shu‐Ting Chen (ORCID: https://orcid.org/0000-0002-6892-5726)
- S.-H. Tseng
Institutions
- Fu Jen Catholic University (TW)
- National Yang Ming Chiao Tung University (TW)
- Taipei Veterans General Hospital (TW)
- Mayo Clinic in Arizona (US)
- University College London (GB)
Publication Details
- Journal
- The Journal of Headache and Pain
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1186/s10194-025-02209-7
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Taipei Veterans General Hospital
- National Science and Technology Council