Circulating biomarkers associated with pyroptosis in the differential diagnosis of ST-segment elevation and non-ST-segment elevation myocardial infarction
NLRP3 inflammasome may play a role in the production of pro-inflammatory cytokines such as IL-1β and IL-18 in STEMI. Inflammasome-related biomarkers show potential as adjunctive tools for distinguishing between STEMI and NSTEMI; however, further studies with multiple timepoints and larger sample sizes are needed to confirm their diagnostic utility and clinical applicability.
Authors
- Adem Melekoglu
- Ertuğrul Altınbilek (ORCID: https://orcid.org/0000-0003-4201-8850)
- Zeki Doğan (ORCID: https://orcid.org/0000-0002-5620-7268)
- Ufuk Çakatay
- Nedim Uzun (ORCID: https://orcid.org/0000-0001-9593-5869)
- Naile Fevziye Mısırlıoglu (ORCID: https://orcid.org/0009-0007-4735-4091)
- Sidar Şiyar Aydın (ORCID: https://orcid.org/0000-0002-8204-1505)
- Hafize Uzun
- Şeyma Dümür (ORCID: https://orcid.org/0000-0001-8893-2926)
- Abdulhalim Senyigit
Institutions
- Directorate of Health (IS)
- Istanbul University-Cerrahpaşa (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- Gaziosmanpaşa Taksim Eğitim ve Araştırma Hastanesi (TR)
- Şişli Etfal Eğitim ve Araştırma Hastanesi (TR)
- Istanbul University (TR)
- University of Health Sciences Antigua (AG)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-11-25
- DOI
- https://doi.org/10.3389/fcvm.2025.1648568
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00