Cervicovaginal microbiome alters transcriptomic and chromatin accessibility signatures across cervicovaginal epithelial barriers
These results provide new insights into host-microbe interactions within the lower reproductive tract and suggest that modulating the cervicovaginal microbiome could offer innovative therapeutic strategies to improve reproductive health. Video Abstract.
Authors
- Briana Ferguson
- Lauren Anton (ORCID: https://orcid.org/0000-0003-2860-6162)
- Michal A. Elovitz (ORCID: https://orcid.org/0000-0001-7554-7180)
- Jacques Ravel (ORCID: https://orcid.org/0000-0002-0851-2233)
- Ana G. Cristancho (ORCID: https://orcid.org/0000-0001-9250-8757)
Institutions
- University of Maryland, Baltimore (US)
- Children's Hospital of Philadelphia (US)
- Institute for Learning Innovation (US)
- International Women's Health Coalition (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Microbiome
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1186/s40168-025-02223-6
- Citations
- 1
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 1.18