6-Aminonicotinamide enhances the efficacy of 5-aminolevulinic acid-mediated photodynamic therapy for neuroblastoma
6-AN enhances the cytotoxicity of 5-ALA-mediated PDT and promotes membrane lipid peroxidation in neuroblastoma cells. 5-ALA-mediated PDT combined with 6-AN could be a potential treatment strategy for neuroblastoma.
Authors
- Zayar Linn (ORCID: https://orcid.org/0000-0003-1232-3731)
- Vipin Shankar Chelakkot (ORCID: https://orcid.org/0000-0002-2385-9489)
- Hiroki Hori (ORCID: https://orcid.org/0000-0003-0030-3530)
- Kengo Nakahata
- Hidemi Toyoda (ORCID: https://orcid.org/0000-0002-4727-6050)
- Yoko Onishi
- Satoshi Okamura (ORCID: https://orcid.org/0000-0001-7885-6501)
Institutions
- Suzuka University of Medical Science (JP)
- Mie University (JP)
- Cleveland Clinic Lerner College of Medicine (US)
- Nishinomiya Municipal Central Hospital (JP)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1186/s12885-025-15231-4
- Primary Topic
- Photodynamic Therapy Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science