The Combination of Diosgenin, Vitamin D, and α-Lactalbumin Normalizes the Menstrual Cycle in Women with PCOS of Phenotype D: A Pilot Clinical Study

The combination of <i>Dioscorea villosa</i>, vitamin D, and α-lactalbumin promotes menstrual cycle regularization in women with PCOS phenotype D. The positive result suggests a beneficial role of the treatment when administered to this specific subtype of PCOS and supports the use of targeted nutraceutical therapy as an alternative to conventional treatments, especially in non-hyperandrogenic PCOS patients.

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Publication Details

Journal
Nutrients
Published
2025-11-25
DOI
https://doi.org/10.3390/nu17233695
Primary Topic
Ovarian function and disorders
Type
article
Field-Weighted Citation Impact
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article

The Combination of Diosgenin, Vitamin D, and α-Lactalbumin Normalizes the Menstrual Cycle in Women with PCOS of Phenotype D: A Pilot Clinical Study

Gabriele Bilotta, Michele Russo, Giuseppina Porcaro, Vittorio Unfer et al.
Nutrients
Ovarian function and disorders
article

The Combination of Diosgenin, Vitamin D, and α-Lactalbumin Normalizes the Menstrual Cycle in Women with PCOS of Phenotype D: A Pilot Clinical Study

Gabriele Bilotta, Michele Russo, Giuseppina Porcaro, Vittorio Unfer, Cesare Aragona, M. Di Liberto
article en

Abstract

The combination of <i>Dioscorea villosa</i>, vitamin D, and α-lactalbumin promotes menstrual cycle regularization in women with PCOS phenotype D. The positive result suggests a beneficial role of the treatment when administered to this specific subtype of PCOS and supports the use of targeted nutraceutical therapy as an alternative to conventional treatments, especially in non-hyperandrogenic PCOS patients.

NutrientsVol. 17(23)
Ospedale Santa Chiara (IT), Saint Camillus International University of Health and Medical Sciences (IT), SIPN S.R.L. (Italy) (IT), Centro Clinico Nemo (IT), European Gravitational Observatory (IT), Sapienza University of Rome (IT)
Openalex Percentile: Top 54%
Ovarian function and disorders
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