Development and application of quality assurance methods for interventions in randomised controlled trials of surgical oncology: the ROMIO study (a comparison of minimally invasive and open oesophagectomy)
Embedding QA measures into pragmatic surgical cancer RCTs is feasible, and provides important data about the quality of interventions. Methods to streamline data collection and analyses are needed prior to widespread use.
Authors
- Renol Koshy (ORCID: https://orcid.org/0000-0002-2330-0589)
- James Byrne (ORCID: https://orcid.org/0000-0003-3517-5110)
- Marcus Jepson (ORCID: https://orcid.org/0000-0003-3261-1626)
- Chris Rogers (ORCID: https://orcid.org/0000-0002-9624-2615)
- Simon Dwerryhouse
- Adam Peckham-Cooper (ORCID: https://orcid.org/0000-0001-5660-5314)
- Rhys C. Jones (ORCID: https://orcid.org/0000-0002-0235-2996)
- Tim Underwood (ORCID: https://orcid.org/0000-0001-9455-2188)
- Lee Humphreys (ORCID: https://orcid.org/0000-0002-5005-0394)
- Anni King (ORCID: https://orcid.org/0000-0002-4489-0864)
- Richard Berrisford
- Kerry Avery (ORCID: https://orcid.org/0000-0001-5477-2418)
- Steven Hornby
- Jamie Kelly (ORCID: https://orcid.org/0009-0007-3892-5497)
- Graeme Couper (ORCID: https://orcid.org/0009-0008-0089-1065)
- Arfon Powell (ORCID: https://orcid.org/0000-0002-3740-8275)
- Beverly A. Shirkey (ORCID: https://orcid.org/0000-0002-4347-6784)
- Natalie Blencowe (ORCID: https://orcid.org/0000-0002-6111-2175)
- Daisy Gaunt (ORCID: https://orcid.org/0000-0002-1253-307X)
- Jane M. Blazeby (ORCID: https://orcid.org/0000-0002-3354-3330)
- Fergus Noble (ORCID: https://orcid.org/0009-0007-0870-9742)
- Bilal Alkhaffaf (ORCID: https://orcid.org/0000-0001-5751-1846)
- Peter Lamb (ORCID: https://orcid.org/0000-0002-3985-4041)
- David Exon
- Alex Boddy (ORCID: https://orcid.org/0000-0001-7243-0155)
- William Hollingworth (ORCID: https://orcid.org/0000-0002-0840-6254)
- Khurshid Akhtar (ORCID: https://orcid.org/0000-0002-1487-4839)
- Ali Güner (ORCID: https://orcid.org/0000-0001-7801-8081)
- Chris Metcalfe (ORCID: https://orcid.org/0000-0001-8318-8907)
- Richard J. E. Skipworth (ORCID: https://orcid.org/0000-0003-1428-4078)
- H. Porter
- Lucy A. Culliford (ORCID: https://orcid.org/0000-0002-9255-6617)
- Daisy Elliott (ORCID: https://orcid.org/0000-0001-8143-9549)
- Newton A C S Wong (ORCID: https://orcid.org/0000-0002-9537-4106)
- Neil T. Welch
- James Catton
- Paul Turner (ORCID: https://orcid.org/0000-0001-9862-5161)
- Tanvir Hossain (ORCID: https://orcid.org/0000-0001-5203-928X)
- William B. Robb
- Andrew D. Hollowood
- Chris Deans
- David Bowrey
- S. S. Ubhi
- Christopher G. Streets
- Rachel C. M. Brierley (ORCID: https://orcid.org/0000-0001-9993-6498)
- B. Howes
- Ravinder Vohra
- Arun Ariyarathenam
- Tim Wheatley
- Richard Krysztopik
- C P Barham
- George B. Hanna
- Rachel Melhado
- Vinutha Shetty
- Grant Sanders
- Simon L. Parsons
- Paul M Wilkerson
- Simon Higgs
- Naheed Farooq
- Kishore Pursnani
- Ram Chaparala
- Jenny L. Donovan
- A. Paisley
- Martin Wadley
- Rob Williams
Institutions
- Lancashire Teaching Hospitals NHS Foundation Trust (GB)
- Cardiff and Vale University Health Board (GB)
- North Bristol NHS Trust (GB)
- Nottingham University Hospitals NHS Trust (GB)
- Karadeniz Technical University (TR)
- University of the West of England (GB)
- Leicester Royal Infirmary (GB)
- Royal Victoria Infirmary (GB)
- University Hospitals Bristol NHS Foundation Trust (GB)
- St James's University Hospital (GB)
- At Bristol (GB)
- Beaumont Hospital (IE)
- Edinburgh Royal Infirmary (GB)
- University Hospital Southampton NHS Foundation Trust (GB)
- South Tees Hospitals NHS Foundation Trust (GB)
- University of Bristol (GB)
- NIHR Bristol Biomedical Research Centre (GB)
- Gloucestershire Royal Hospital (GB)
- University Hospitals Plymouth NHS Trust (GB)
- University Hospitals Bristol and Weston NHS Foundation Trust (GB)
- Imperial College London (GB)
- University of Salford (GB)
Publication Details
- Journal
- British Journal of Cancer
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1038/s41416-025-03236-6
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- United Kingdom Clinical Research Collaboration
- University Hospitals Bristol NHS Foundation Trust
- National Institute for Health and Care Research
- Department of Health and Social Care
- University of Bristol
- Medical Research Council