Evaluation of the TARGET score for MRI-based detection of prostate cancer recurrence in patients treated with HIFU hemiablation

The strength of the TARGET score was its high NPV, implying its potential to rule out cs-PCa. However, the moderate sensitivity and specificity, low PPV and moderate inter-reader agreement indicate a limited reliability of TARGET to consistently identify cs-PCa recurrence. The generalizability of these findings is restricted by the overall small sample size.

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Publication Details

Journal
European Journal of Radiology
Published
2025-11-25
DOI
https://doi.org/10.1016/j.ejrad.2025.112572
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Evaluation of the TARGET score for MRI-based detection of prostate cancer recurrence in patients treated with HIFU hemiablation

Roman Ganzer, Sebastian Ebel, Nilüfer Deniz Alberalar, Alexander Schaudinn et al.
European Journal of Radiology
Prostate Cancer Diagnosis and Treatment
article

Evaluation of the TARGET score for MRI-based detection of prostate cancer recurrence in patients treated with HIFU hemiablation

Roman Ganzer, Sebastian Ebel, Nilüfer Deniz Alberalar, Alexander Schaudinn, Lars‐Christian Horn, Boris Hadaschik, Constantin Ehrengut, Andreas Blana, Toni Franz, Jens‐Uwe Stolzenburg, H Schlemmer, Timm°Denecke
article en

Abstract

The strength of the TARGET score was its high NPV, implying its potential to rule out cs-PCa. However, the moderate sensitivity and specificity, low PPV and moderate inter-reader agreement indicate a limited reliability of TARGET to consistently identify cs-PCa recurrence. The generalizability of these findings is restricted by the overall small sample size.

European Journal of RadiologyVol. 195
German Cancer Research Center (DE), Heidelberg University (DE), University Hospital Leipzig (DE), Klinikum Fürth (DE), Asklepios (DE), Leipzig University (DE)
Openalex Percentile: Top 46%
Prostate Cancer Diagnosis and Treatment
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Evaluation of the TARGET score for MRI-based detection of prostate cancer recurrence in patients treated with HIFU hemiablation — Roman Ganzer, Sebastian Ebel, et al. · European Journal of Radiology (2025) | TGRS Research Map | TGRS