Patient-Centred and Daily Life-Oriented Botulinum Toxin Treatment for Stroke Survivors with Upper Extremity Spasticity—Effects and Practical Aspects
The Resistance to Passive Movement Scale (REPAS), Motricity Index (MI), SF-12v2 Health Survey (SF-12v2), Global Clinical Impression (GCI), and importance of and satisfaction with the BoNT-A treatment. <b>Results</b>: Performance of individually selected daily activities and satisfaction with their performance (COPM), passive care tasks (ArmA, part A), and resistance to passive movement (REPAS) significantly improved from T0 to Tmax1. Improvements largely remained at T2. Individual goals were all set at the activities and participation levels of the International Classification of Functioning, Disability and Health. These improved for 75% of participants and were fully attained by 33.3% at Tmax1. Responder analysis indicated that COPM and ArmA improvements were clinically significant for up to 50% of participants. Active upper extremity use (ArmA, part B), health-related quality of life (SF-12v2), and upper extremity strength (MI) remained unchanged. <b>Conclusions</b>: Our results indicate that BoNT-A in combination with routine outpatient therapy positively influenced the individually valued daily activities of stroke survivors. COPM, GAS, and ArmA are suitable for facilitating a patient-centred and daily life-oriented spasticity management post-stroke.
Authors
- T. David Punt (ORCID: https://orcid.org/0000-0003-2384-3193)
- Thomas Platz (ORCID: https://orcid.org/0000-0003-2629-9744)
- Sybille Roschka (ORCID: https://orcid.org/0000-0001-5987-9679)
Institutions
- Universitätsmedizin Greifswald (DE)
- University of Birmingham (GB)
Publication Details
- Journal
- Journal of Clinical Medicine
- Published
- 2025-11-24
- DOI
- https://doi.org/10.3390/jcm14238339
- Primary Topic
- Botulinum Toxin and Related Neurological Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00