Burden of sickle cell anemia in Africa: A systematic review and meta-analysis
SCA represents a substantial and geographically variable public health challenge across Africa. These findings highlight the need for region-specific interventions, expanded newborn screening programs, improved diagnostic accessibility with quality assurance for point-of-care technologies, and continued surveillance to address geographic gaps.
Authors
- Gerald Mboowa (ORCID: https://orcid.org/0000-0001-8445-9414)
- Felix Bongomin (ORCID: https://orcid.org/0000-0003-4515-8517)
- Richard Kwizera (ORCID: https://orcid.org/0000-0002-5270-3539)
- Bram Herman
- S. Stephen (ORCID: https://orcid.org/0000-0002-1104-133X)
- Bwambale Jonani (ORCID: https://orcid.org/0009-0000-9719-3934)
- John Bosco Mundaka
- Emmanuel Charles Kasule (ORCID: https://orcid.org/0000-0001-7156-2594)
- Joel Fredrick Arturo
- Mwesigwa Calvin Mugambwa
Institutions
- Gulu University (UG)
- African Bible University (UG)
- Infectious Diseases Institute (UG)
- Makerere University (UG)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1371/journal.pone.0337090
- Citations
- 3
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 4.88