Shift work is associated with selective brain volume loss: a longitudinal study
Shift workers have selective volume loss of the thalamus and amygdala, which is halted within 2.4 years of stopping shift work. Monitoring, counselling and interventional measures, including adjustment of work schedules, could minimise brain volume loss in shift workers.
Authors
- Ling Ling Chan (ORCID: https://orcid.org/0000-0001-7603-7334)
- Eng‐King Tan (ORCID: https://orcid.org/0000-0003-2977-9743)
- Thomas Welton (ORCID: https://orcid.org/0000-0002-9503-2093)
- Thomas Wei Jun Teo (ORCID: https://orcid.org/0009-0006-7518-677X)
- Seyed Ehsan Saffari
Institutions
- SingHealth (SG)
- Singapore General Hospital (SG)
- Duke-NUS Medical School (SG)
- National Neuroscience Institute (SG)
Publication Details
- Journal
- NeuroImage
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1016/j.neuroimage.2025.121619
- Primary Topic
- Sleep and Work-Related Fatigue
- Type
- article
- Field-Weighted Citation Impact
- 0.00