Cancer cell-dependent increase in senescence-like populations following exosome treatment from bone marrow and induced pluripotent stem cell-derived mesenchymal stem cells
iMSC-Exos effectively inhibited tumor proliferation and invasion <i>via</i> a senescence-like mechanism. These results indicated that iMSC-Exos could serve as a cell-free cancer therapy and merit further animal model evaluation.
Authors
- Anas H. A. Abu-Humaidan (ORCID: https://orcid.org/0000-0003-1739-6948)
- Ahmed Abdulelah (ORCID: https://orcid.org/0000-0001-9474-1106)
- Tareq Saleh (ORCID: https://orcid.org/0000-0002-2878-1107)
- Nidaa A. Ababneh (ORCID: https://orcid.org/0000-0002-2155-3013)
- Abdalla Awidi
- Khairallah Al-Abdallat
- Talal Salem Al‐Qaisi (ORCID: https://orcid.org/0000-0002-3646-657X)
- Mohammad A. Ismail (ORCID: https://orcid.org/0000-0001-5039-8764)
- Razan AlDiqs
- Sura Nashwan (ORCID: https://orcid.org/0000-0003-1374-4378)
- Lina AlQirem
Institutions
- Al-Ahliyya Amman University (JO)
- University of Jordan (JO)
- Abu Dhabi University (AE)
- Hashemite University (JO)
- Jordan Hospital (JO)
Publication Details
- Journal
- World Journal of Stem Cells
- Published
- 2025-11-26
- DOI
- https://doi.org/10.4252/wjsc.v17.i11.110381
- Citations
- 1
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 1.16