Fidelity-preserving enhancement of ptychography with foundational text-to-image models

Ptychographic phase retrieval enables high-resolution imaging of complex samples but often suffers from artifacts such as grid pathology and multislice crosstalk, which degrade reconstructed images. We propose a plug-and-play (PnP) framework that integrates physics model-based phase retrieval with text-guided image editing using foundational diffusion models. By employing the alternating direction method of multipliers, our approach ensures consensus between data fidelity and artifact removal subproblems, maintaining physical consistency while enhancing image quality. Artifact removal is achieved using a text-guided diffusion image editing method (LEDITS++) with a pre-trained foundational diffusion model, allowing users to specify artifacts for removal in natural language. Demonstrations on simulated and experimental datasets show significant improvements in artifact suppression and structural fidelity, validated by metrics such as peak signal-to-noise ratio and diffraction pattern consistency. This work highlights the combination of text-guided generative models and model-based phase retrieval algorithms as a transferable and fidelity-preserving method for high-quality diffraction imaging.

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Publication Details

Journal
Optica
Published
2025-11-26
DOI
https://doi.org/10.1364/optica.579456
Primary Topic
Advanced X-ray Imaging Techniques
Type
article
Field-Weighted Citation Impact
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article

Fidelity-preserving enhancement of ptychography with foundational text-to-image models

Junjing Deng, Dileep Kumar Singh, Mathew J. Cherukara, Volker Rose et al.
Optica
Advanced X-ray Imaging Techniques
article

Fidelity-preserving enhancement of ptychography with foundational text-to-image models

Junjing Deng, Dileep Kumar Singh, Mathew J. Cherukara, Volker Rose, Si Chen, Ming Du
article en

Abstract

Ptychographic phase retrieval enables high-resolution imaging of complex samples but often suffers from artifacts such as grid pathology and multislice crosstalk, which degrade reconstructed images. We propose a plug-and-play (PnP) framework that integrates physics model-based phase retrieval with text-guided image editing using foundational diffusion models. By employing the alternating direction method of multipliers, our approach ensures consensus between data fidelity and artifact removal subproblems, maintaining physical consistency while enhancing image quality. Artifact removal is achieved using a text-guided diffusion image editing method (LEDITS++) with a pre-trained foundational diffusion model, allowing users to specify artifacts for removal in natural language. Demonstrations on simulated and experimental datasets show significant improvements in artifact suppression and structural fidelity, validated by metrics such as peak signal-to-noise ratio and diffraction pattern consistency. This work highlights the combination of text-guided generative models and model-based phase retrieval algorithms as a transferable and fidelity-preserving method for high-quality diffraction imaging.

OpticaVol. 13(1)
Argonne National Laboratory (US)
Openalex Percentile: Top 54%
Advanced X-ray Imaging Techniques
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