Antinociceptive efficacy, chemistry, potential toxicity, and quality control procedures of Clinopodium macrostemum and Clinopodium mexicanum: A comparative analysis
The observed antinociceptive activity in both Clinopodium species is consistent with their reported pharmacological potential and traditional use. However, the acute renal injury associated with both plants requires further investigation. In contrast, variability in the volatilome between species may serve as a valuable tool for quality control. These differences in chemical composition suggest key avenues for distinguishing and effectively utilizing the species.
Authors
- Omar Emiliano Aparicio‐Trejo (ORCID: https://orcid.org/0000-0002-7701-4537)
- Isabel Rivero‐Cruz (ORCID: https://orcid.org/0000-0003-0185-5775)
- Rachel Mata (ORCID: https://orcid.org/0000-0002-2861-2768)
- Sol Cristians (ORCID: https://orcid.org/0000-0002-0104-4852)
- Valeria Reyes‐Pérez (ORCID: https://orcid.org/0000-0002-5535-7627)
- Gabriela García‐Marín
Institutions
- Universidad Autónoma de la Ciudad de México (MX)
- Instituto Nacional de Cardiologia (BR)
- Instituto Nacional de Cardiología (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1016/j.jep.2025.120951
- Primary Topic
- Plant chemical constituents analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00