Smaller Quadriceps Size Is Associated with Lower Exercise Capacity and Greater Disease Severity in People with Fibrotic Interstitial Lung Disease

In fibrotic ILD, those with smaller quadriceps muscle size have lower exercise capacity and worse lung function. This is more apparent in those who experience exertional desaturation. Identifying interventions that preserve quadriceps muscle size in fibrotic ILD would prove beneficial.

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Publication Details

Journal
Medicine & Science in Sports & Exercise
Published
2025-11-25
DOI
https://doi.org/10.1249/mss.0000000000003899
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
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article

Smaller Quadriceps Size Is Associated with Lower Exercise Capacity and Greater Disease Severity in People with Fibrotic Interstitial Lung Disease

Anne E. Holland, Anthony K. May, James Walsh, Janet Bondarenko et al.
Medicine & Science in Sports & Exercise
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

Smaller Quadriceps Size Is Associated with Lower Exercise Capacity and Greater Disease Severity in People with Fibrotic Interstitial Lung Disease

Anne E. Holland, Anthony K. May, James Walsh, Janet Bondarenko, Leona Dowman, Norman Morris, Catherine J. Hill, Kate Hayes
article en

Abstract

In fibrotic ILD, those with smaller quadriceps muscle size have lower exercise capacity and worse lung function. This is more apparent in those who experience exertional desaturation. Identifying interventions that preserve quadriceps muscle size in fibrotic ILD would prove beneficial.

Medicine & Science in Sports & ExerciseVol. 58(4)
Griffith University (AU), Monash Alfred Psychiatry Research centre (AU), Institute for Breathing and Sleep (AU), Prince Charles Hospital (AU), Alfred Health (AU), Austin Health (AU), Monash University (AU)
Openalex Percentile: Top 46%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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