25-Hydroxyvitamin D Deficiency in the First Trimester Is Associated with Increased Obstetric Complications despite Standard Supplementation during Pregnancy
First-trimester 25(OH)D<sub>3</sub> sufficiency was associated with reduced risk of obstetric complications, compared with women with insufficiency, even when the last achieved sufficiency in the second and third trimester. These findings highlight the importance of early screening and support the need for personalized supplementation strategies before conception to optimize maternal-fetal outcomes.
Authors
- Dalia Gutiérrez-González (ORCID: https://orcid.org/0009-0002-8160-3681)
- Arnulfo Garza‐Silva (ORCID: https://orcid.org/0000-0002-2200-1958)
- María Elena Romero-Ibarguengoitia (ORCID: https://orcid.org/0000-0002-2572-4043)
- Iván Francisco Fernández‐Chau (ORCID: https://orcid.org/0009-0007-4423-2814)
- Rafael Gámez
- Maria Fernanda Lozano-Martínez
- Ana Sofía Sánchez-García
Institutions
- University of Monterrey (MX)
Publication Details
- Journal
- Gynecologic and Obstetric Investigation
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1159/000549513
- Primary Topic
- Vitamin D Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00