Revisiting the FAITH Trial: A Secondary Analysis Yielding Novel Insights with the Win Ratio
This analysis approach should be considered for future orthopaedic trials as it was consistent with the FAITH primary analysis findings but yielded a more nuanced interpretation of the patients' experience and offers deeper insights into intervention effectiveness. The bounds of the 95% CI for the primary outcome were within many standard definitions of equivalence, suggesting surgeons can assume similar patient-important outcomes with either treatment.
Authors
- Sofia Bzovsky (ORCID: https://orcid.org/0000-0003-3505-1396)
- Graeme Hoit (ORCID: https://orcid.org/0000-0001-5114-6999)
- Kiara Pannozzo (ORCID: https://orcid.org/0009-0000-2044-1477)
- Nathan N. O’Hara (ORCID: https://orcid.org/0000-0003-0537-3474)
- Daniel Axelrod (ORCID: https://orcid.org/0000-0002-0460-1298)
- Rudolf W. Poolman (ORCID: https://orcid.org/0000-0003-3178-2247)
- Sheila Sprague (ORCID: https://orcid.org/0000-0003-1466-8063)
- Gerard P. Slobogean (ORCID: https://orcid.org/0000-0002-9111-9239)
- Emil H. Schemitsch (ORCID: https://orcid.org/0000-0002-6435-9069)
- M.F. Swiontkowski (ORCID: https://orcid.org/0000-0001-7036-1782)
- Mohit Bhandari
Institutions
- Western University (CA)
- University of Maryland, Baltimore (US)
- University of Minnesota (US)
- Canadian Institutes of Health Research (CA)
- University of Toronto (CA)
- University of California, Irvine (US)
- Leiden University Medical Center (NL)
- Impact (CA)
- Joint Research Centre (NL)
- McMaster University (CA)
Publication Details
- Journal
- JBJS Open Access
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2106/jbjs.oa.25.00230
- Primary Topic
- Meta-analysis and systematic reviews
- Type
- article
- Field-Weighted Citation Impact
- 0.00