Oncocytic Adrenocortical Carcinoma in an Infant

Pediatric adrenocortical carcinoma (ACC) is rare malignancy, and its oncocytic variant is exceptionally rare in infants. A 1-year-old girl presented with excessive hair growth and hoarseness of voice for 8 months of age. Investigations revealed elevated androgen levels, and whole-body 18F FDG PET-CT imaging showed an isolated large left adrenal mass. The mass was surgically excised, and histopathology confirmed oncocytic adrenocortical carcinoma with a Wieneke score of 5, indicating malignancy. The postoperative course was uneventful with stabilization on antihypertensive and corticosteroid therapy.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2025-11-07
DOI
https://doi.org/10.1097/rlu.0000000000006208
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
Field-Weighted Citation Impact
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Oncocytic Adrenocortical Carcinoma in an Infant

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Adrenal and Paraganglionic Tumors
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Oncocytic Adrenocortical Carcinoma in an Infant

Tarun Kumar Jain, Atul Gupta, Kamla Kant Shukla, Lalit Mohan Sharma, Maneesh Kumar Vijay, Patel Meet
article en

Abstract

Pediatric adrenocortical carcinoma (ACC) is rare malignancy, and its oncocytic variant is exceptionally rare in infants. A 1-year-old girl presented with excessive hair growth and hoarseness of voice for 8 months of age. Investigations revealed elevated androgen levels, and whole-body 18F FDG PET-CT imaging showed an isolated large left adrenal mass. The mass was surgically excised, and histopathology confirmed oncocytic adrenocortical carcinoma with a Wieneke score of 5, indicating malignancy. The postoperative course was uneventful with stabilization on antihypertensive and corticosteroid therapy.

Clinical Nuclear Medicine
Gandhi Medical College & Hospital (IN), Mahatma Gandhi Mission Medical College and Hospital (IN)
Openalex Percentile: Top 45%
Adrenal and Paraganglionic Tumors
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