Serotype diversity and risk factors for pneumococcal carriage among healthy children in Klang Valley, Malaysia: A pre-vaccination cross-sectional study
This study provides crucial pre-PCV baseline data on pneumococcal carriage, serotype diversity, and risk factors in children of Klang Valley, Malaysia. The high prevalence of NVTs and frequent co-colonization highlight the need for ongoing surveillance to detect serotype replacement and guide evaluation of higher-valency PCVs. These findings can inform national immunization policy and strengthen strategies for monitoring vaccine impact in Malaysia.
Authors
- Revathy Arushothy (ORCID: https://orcid.org/0000-0001-8259-7143)
- Saraswathiy Maniam
- Salina Mohamed Sukur
- Ratna Mohd Tap (ORCID: https://orcid.org/0000-0002-9288-8988)
- Nur Asyura Nor Amdan (ORCID: https://orcid.org/0000-0002-8150-8601)
- Mohammad Ridhuan Mohd Ali (ORCID: https://orcid.org/0000-0002-5888-3526)
- Rohaidah Hashim (ORCID: https://orcid.org/0000-0002-4314-9177)
- Li Ling (ORCID: https://orcid.org/0000-0003-3292-274X)
- Prem Ananth Paliappan
- Tan Cheng Ngee
Institutions
- Ministry of Health (MY)
- Sultanah Aminah Hospital (MY)
- University of Malaya (MY)
Publication Details
- Journal
- IJID Regions
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1016/j.ijregi.2025.100814
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00